| # | Name | Rank | Elevation | Prominence | Counties | Quadrangle |
| 1 | Clingmans Dome | 1 | 6,645' | 4,512' | Sevier & Swain | Clingmans Dome |
| 2 | Roan High Knob | 5 | 6,285' | 3,505' | Carter & Mitchell | Carvers Gap |
| 3 | Big Bald | 12 | 5,516' | 2,576' | Unicoi & Yancey | Bald Creek |
| 4 | Holston High Point | 54 | 4,300' | 1,630' | Carter & Sullivan | Keenburg |
| 5 | Rye Patch Knob | 60 | 4,260' | 320' | Carter & Sullivan | Carter |