| # | Name | Rank | Elevation | Prominence | Counties | Quadrangle |
| 1 | Mitchell, Mount | 1 | 6,684' | 6,090' | Yancey | Mount Mitchell |
| 2 | Clingmans Dome | 3 | 6,645' | 4,512' | Sevier & Swain | Clingmans Dome |
| 3 | Richland Balsam | 8 | 6,410' | 3,030' | Haywood & Jackson | Sam Knob |
| 4 | Roan High Knob | 12 | 6,285' | 3,505' | Carter & Mitchell | Carvers Gap |
| 5 | Sassafras Mountain | 660 | 3,552' | 766' | Pickens & Transylvania | Eastatoe Gap |